Scientific innovation.
We fund and conduct research to expand what’s known about magnesium L-threonate, including randomized, double-blind, placebo-controlled human trials.
Who Are the Brains Behind Magtein?
Magtein® (magnesium L-threonate) is a patented ingredient studied for brain-focused support. If you’ve seen it on a supplement label, this page explains where it comes from — and who stands behind the science.
Magtein is brought to you by ThreoTech LLC, a manufacturing, marketing, and research company dedicated to commercializing this ingredient. ThreoTech is the exclusive global ingredient supplier and patent licensee for Magtein, supporting its quality and authenticity.
If you don’t see Magtein on the label, it isn’t an authentic product — it wasn’t made using ThreoTech’s patented process.
The Science Behind Magtein
Magtein began with the research of Dr. Guosong Liu, a neuroscientist who studied how magnesium supports brain function. A former faculty member in brain and cognitive sciences at the Massachusetts Institute of Technology, Dr. Liu has spent much of his career investigating the role of magnesium in synaptic density, plasticity, learning, and memory — research that led to the development of magnesium L-threonate, the brain-bioavailable form branded as Magtein. His foundational work on elevating brain magnesium to support cognition continues to guide Magtein’s ongoing clinical program.
Regulatory Authorizations
Magnesium L-threonate has been reviewed and authorized by regulators in multiple major markets:
- United States
- European Union
- United Kingdom
- Canada
- Brazil
- India
- Thailand
What ThreoTech Is Committed To
Quality and safety.
Our patented production process is designed to meet quality, safety, and regulatory requirements across global markets, including FDA, EU, and UK authorization.
Global availability.
Magtein is used in hundreds of products worldwide, through partnerships with leading supplement brands.
Frequently Asked Questions
What is Magtein?
Magtein® is a patented, branded form of magnesium L-threonate — a form of magnesium studied for brain-focused support. It’s manufactured and distributed exclusively by ThreoTech LLC.
Who makes Magtein?
Magtein is made by ThreoTech LLC, the exclusive global ingredient supplier and patent licensee. Every supplement brand selling Magtein sources the raw ingredient from ThreoTech.
Is Magtein the same as magnesium L-threonate?
Magtein is the patented, branded form of magnesium L-threonate produced by ThreoTech. Products claiming to contain magnesium L-threonate without the Magtein name are not made under our patented process and are not authorized. If a label doesn’t say Magtein, it isn’t Magtein.
Who is on Magtein’s Scientific Advisory Board?
The board includes Dr. Thomas C. Südhof (Stanford University, 2013 Nobel Laureate), Dr. Jack L. Feldman (UCLA), and Dr. Guosong Liu, the scientist who developed magnesium L-threonate.
Is Magtein safe?
Yes. Magtein holds a U.S. FDA GRAS notification and novel-food authorizations in the EU and UK and is approved for use in supplement products in Canada, Brazil, Thailand, and India.
Is Magtein approved by regulators?
Magnesium L-threonate holds a U.S. FDA GRAS notification (No. 499), EU novel-food authorization (Commission Implementing Regulation (EU) 2024/2694), and UK Food Standards Agency novel-food authorization (RP-956), and is also approved for use in food supplement products in Canada, Brazil, Thailand, and India.
For Brands and Manufacturers
Formulating with Magtein means working with a clinically studied ingredient, a documented supply chain, and a research program that keeps growing. If you’re developing in cognitive health, sleep, or healthy aging, get in touch.
Questions?
We’re happy to answer them. Contact us.
Our scientific advisors advise on research direction and methodology; they do not evaluate or endorse finished products. Dr. Südhof and Dr. Feldman hold equity in Neurocentria Inc., which owns the patents licensed to ThreoTech for Magtein, and Dr. Südhof is compensated for his advisory role. Dr. Liu, the developer of Magtein, is a part owner of ThreoTech. These statements have not been evaluated by the Food and Drug Administration. Magtein is not intended to diagnose, treat, cure, or prevent any disease.