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The Magtein Original Inventor’s Formula is the only product used in the clinical research, conducted by the MIT researcher. Following years of evaluation, a 12-week randomized, double-blind, placebo-controlled human clinical study was published in 2016 in the prestigious Journal of Alzheimer’s Disease.
Improves Brain Function*
Magtein was evaluated in a series of cognitive tests within four major domains of the brain: executive function, working memory, attention and episodic memory.
A composite score was calculated from this series of tests to provide an overall assessment of change in cognitive abilities throughout the course of the 12-week study. The Magtein supplemented group demonstrated significant improvements in composite score at 6 weeks (p<0.05) and 12 weeks (p<0.01), relative to placebo. (Figure 1)
A composite score was calculated from this series of tests to provide an overall assessment of change in cognitive abilities throughout the course of the 12-week study. The Magtein supplemented group demonstrated significant improvements in composite score at 6 weeks (p<0.05) and 12 weeks (p<0.01), relative to placebo. (Figure 1)


Reduces "Brain Age"*
The most striking finding of this Magtein Inventor’s Formula human trial was an improvement in executive function. This improvement is equivalent to a nine-year reduction in "brain age" with just 12 weeks of supplementation (Figure 2).
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Magceutics Inc. is a nutraceutical company focused on brain health. Our products are built on more than a decade of research from MIT led by the original inventor of Magtein®, a revolutionary magnesium product that crosses the blood-brain barrier and supports improved cognitive functions.
Magtein is the only magnesium shown to effectively enter the brain*
Magtein has a higher brain bioavailability when compared to other sources of magnesium, as demonstrated by higher absorption and higher retention.*
Magtein Improves learning and memory*
Magtein has been shown to be the only magnesium compound effective in significantly increasing magnesium concentrations in the brain, and thus improving learning capacity, short- and long-term memory, working memory and synaptic connections in patients of all ages.*
Magtein Improves attention and mood*
Studies suggest long-term elevation of brain magnesium can help enhance synaptic plasticity in brain regions involved with stress and mood.* In-vivo data suggests Magtein may support coping abilities to stressful events and support emotional responses to fear and anxiety.*
Magtein was shown to improve cognitive ability*
In a 12-week randomized, double-blind, placebo-controlled human clinical study, the effect of Magtein on cognitive ability was evaluated in four major domains: executive function, working memory, attention and episodic memory. Significant improvements were observed in each of these domains and Magtein was shown to reduce "brain age" by 9 years.*
Magceutics Inc. is a nutraceutical company focused on brain health. Our products are built on more than a decade of research from MIT led by the original inventor of Magtein®, a revolutionary magnesium product that crosses the blood-brain barrier and supports improved cognitive functions.
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Magtein showed a nine-year reduction in "brain age" with just 12 weeks of supplementation.
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Clinical research shows that Magtein supports memory, attention, emotional wellness, and sleep.