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Proprietary, Patented Magnesium Functional Ingredient Improves Learning, Memory

Animal Study shows that AIDP’s High-Bioavailability Magtein™ Is the Only Oral Magnesium to Effectively Cross the BloodBrain Barrier

Los Angeles, CA (July 2011) – Researchers have known for some time that magnesium is essential for proper brain function. Yet because oral magnesium does not sufficiently raise brain magnesium levels, magnesium supplements have been of little use for enhancing cognitive function. Now, a new high-bioavailability magnesium functional ingredient called Magtein™, distributed by leading ingredient supplier AIDP, Inc. (, has been shown in a recent animal study to significantly elevate brain levels of magnesium.* As a result, Magtein markedly improved learning and memory in animals fed the ingredient.

Magnesium is an essential mineral that is a cofactor for over 300 enzymes and is needed for the proper functioning of many systems, including the nervous system. Magtein, or Magnesium Lthreonate, is a magnesium salt of L-threonic acid, a vitamin C metabolite. It was developed by a group of scientists from the Massachusetts Institute of Technology — including Nobel Prize winner Susumu Tonegawa — who wanted to create a highly bioavailable magnesium compound that could significantly increase brain levels of magnesium through dietary supplementation.

“The level of magnesium in the brain is very different from the level of magnesium in the blood,” comments Dr. Jennifer Gu, PhD, Director of Research and Development for AIDP. “The reason is the blood-brain barrier.” Dr. Gu explains that ordinary magnesium can’t pass through this semipermeable membrane, which is very particular about which substances it allows to enter the brain.

“The animal study showed that, unlike other forms of magnesium, however, Magtein has a very high brain bioavailability, meaning it can penetrate the blood-brain barrier and raise brain magnesium levels for long enough to improve cognitive function,” says Dr. Gu.

The results of the recent study on Magtein, published in the highly respected journal Neuron, showed that Magtein increased learning ability, working memory and short- and long-term memory in both young and aged rats.* In addition, Magtein significantly elevated the magnesium concentration of the cerebrospinal fluid, while other forms of magnesium — including magnesium chloride and magnesium citrate — did not.*

As exciting as these results are, the research on Magtein has only just begun. Two additional animal studies are in the process of being published in top journals, and a human clinical trial on Magtein’s effect on memory and cognitive function is currently underway.

Available exclusively through AIDP, Magtein is self-affirmed GRAS and protected by worldwide patents, with seven U.S. patents pending. Tasteless, odorless and colorless, it is easily added to a wide range of dietary supplements, beverages and functional foods aimed at enhancing cognitive function.

About AIDP, Inc.

AIDP has been a trusted source for core functional ingredients since 1996. Specializing in the area of anti-aging for bone, joint and cognitive health, AIDP is established by solid research breakthroughs and proprietary ingredients. AIDP’s mission is to achieve the highest standards in customer satisfaction through cutting-edge product innovation and superior service.

For more information about AIDP, please call (866) 262-6699 or visit For media related inquiries, please contact Rajan De Los Santos of Christie Communications at (805) 9693744 or

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.