MagteinTM Science

Magtein Science

MagteinTM Animal Research

MagteinTM is the only magnesium form to effectively increase the brain's magnesium levels.

Scientists have recently evaluated the ability of both bioavailable organic and inorganic magnesium forms to raise brain magnesium levels. Magnesium concentration in the cerebrospinal fluid was evaluated following treatment with different magnesium compounds, including Magtein and along with the most bioavailable inorganic magnesium (magnesium-chloride), and the most bioavailable organic magnesium (magnesium-gluconate in milk). After 24 days, MagteinTM was the only magnesium compound shown to raise the cerebrospinal fluid magnesium concentration with statistical significance. (Figure 1)

Enhancement of synaptic density by MagteinTM

Previous studies indicate that synaptic connections in the hippocampus decline during aging, and this loss of synaptic connections correlates with impaired memory functions. To further characterize the cellular changes that underline Magtein-induced memory enhancement, researchers also examined the effect of MagteinTM treatment on the density of presynaptic boutons in aged rats. These results indicate that MagteinTM increased the synaptic density in the hippocampus region of the brain. (Figure 2)

synaptic density

Recognition IndexMagteinTM Memory Research

Spacial Memory

Learning and memory are fundamental brain functions affected by dietary and environmental factors. Here, we show that increasing brain magnesium using a newly developed magnesium compound (Magnesium-L-threonate, MagteinTM) leads to the enhancement of learning abilities, working memory, and short- and long-term memory in rats.

MagteinTM improves short- and long-term memory in young and aged animals.

Animals taking different magnesium forms were evaluated for their short-term and long-term memory by a novel object recognition test. Only MagteinTM subjects showed a significant increase in both short- term and long-term memory. (Figure 3)

MagteinTM improves spatial working memory in young and aged animals

Researchers evaluated the spatial long-term memory of young and aged laboratory animals in a T-maze setting. Animals were timed to  see how long it would take them to find the hidden platform based on a spatial strategy. In both age groups, MagteinTM intake led to a statistically higher spacial working memory. In addition, when MagteinTM intake was stopped at day 24 in the aged group, spacial working memory was reduced to the background level after two weeks. When MagteinTM intake was restated at day 60, the effect of MagteinTM on spacial working memory was observed again. (Figure 4)

Additional Research

Ongoing MagteinTM research is continuing to uncover a variety of new applications. This unique form of magnesium is being evaluated by research communities for longevity, sleep, mood and other conditions of aging. For memory and cognitive health, MagteinTM is the category standard. No other magnesium compares. Human studies are currently under development.

Quick Facts

US consumers aged 65 years or older will double in the next 25 years.

Approximately 50 percent of the U.S. population is deficient in magnesium.

The RDA for magnesium is 350-400 milligrams per day.

Magnesium can be found in leafy greens, healthy grains and beans.

Source: Centers for Disease Control and Prevention.



Magtein TestimonialsForty year old female: "Magnesium L-threonate is the most unique form of magnesium. You must read the studies performed on this type of magnesium to appreciate its capabilities."

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