The Market

Frequently Asked Questions

What is Magtein™?

Magtein is Magnesium I-Threonate, a new form of magnesium.

What does Magtein do?

Magtein can help memory and cognitive functions. Cognitive functions include for areas: 1) attention, 2) memory, 3) executive decision, and 4) visual and spatial recognition.

What clinical studies have been completed?

Four published studies exist on Magtein. The list is located on “The Press” and “The Science Page”. The first is an animal study that was published in Neuron, one of the world’s top three scientific neurology journals. In the Neuron paper, Magtein was shown to uniquely increase brain magnesium levels and improve brain function. This article was published in Jan 2010 by a group of scientists at MIT including a Nobel Prize laureate. They showed that by increasing the brain’s magnesium level, Magtein could increase learning ability, working memory, and short- and long-term memory in young and aged rates. They also showed that common magnesium compounds do not effectively improve brain magnesium levels.

In the October 2011 issue of The Journal of Neuroscience, top neuroscientists at Tsinghua University in Beijing, University of Texas, and University of Toronto revealed that by increasing the extracellular magnesium concentration in the brain through a new magnesium compound called Magtein™, the cognitive ability – an essential facility that controls fear and anxiety – is enhanced. This development becomes extremely significant considering anxiety disorders are the most common mental illness in America, affecting 18% of the population.

A research group at Baldwin Wallace University, independently demonstrated that proprietary ingredient Magtein™, which is designed to improve memory, recognition and learning, enhanced the memory lead to the consolidation and retention of conditioned taste aversion (CTA) in rats. The study was led by G. Andrew Mickley, Ph.D. of The Neuroscience Program at Baldwin Wallace University, Berea, Ohio, and published in Pharmacology Biochemistry Behavior, March 6, 2013.

The report, that appeared in the Journal of Neuroscience, (Li, W., et al.), “Elevation of brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer's disease mouse model”, 2013. 33(19): p8423-41.), shows that a recently developed Magnesium L-Threonate compound known as Magtein™, patented and owned by Magceutics, Inc. and exclusively distributed by City of Industry, Calif.-based AIDP, Inc., may prevent cognitive impairment when administered to mice with early stage AD. The treatment was shown to remain effective for at least 16 months. Additionally, Magtein™ significantly improved memory and cognition when given to advanced stage AD mice. Scientists at the Center for Learning and Memory, Tsinghua University, Beijing, have demonstrated a novel therapy for reversing memory decline in mice with Alzheimer’s disease (AD). By increasing brain magnesium levels, they found significant cognitive improvement in advanced stage AD mice. The study is the first to demonstrate a mechanism for reversing cognitive decline for advanced stage AD mice, as well as showing an effective long-term treatment for early stage AD mice.

How does Magtein work?

Magtein is able to pass through the blood brain barrier more effectively than other magnesium forms. Improved brain function is closely associated with the increased synaptic connections in the DG and CA1 sub regions of the Hippocampus that are known to control memory. The clinical research indicated a greater brain synapse density in subjects taking Magtein.

What is the recommended dose?

Based on the animal study, 1g twice a day with a meal should be sufficient. The human study will provide greater insight into dosing.

Are there any side effects?

Magtein is the only product shown to increase brain magnesium. During the first week, common positive indications of effect are a slight drowsiness and a feeling of increased blood flow in the head. Options for reducing these effects are using a half dosage for one week, and then increasing the dosage thereafter, or taking Magtein immediately after dinner or before going to bed. As with any mineral product, people with kidney deficiency should not take this product. A health professional should always be consulted if you have any serious medical issues.

Some individuals have reported dizziness or slight headaches when first taking Magtein. These conditions will go away quickly after the brain adjusts to the change. Beginning with a reduced dosage and gradually increasing to the proper dosage, may provide a more comfortable transition. It is advised to take it after dinner or before going to bed when first using this product. As always, a doctor should be consulted when starting a new regime.

How long should it be taken?

The animal study showed when subjects were taken off Magtein, the brain synapses began to decline again. For those with ongoing cognitive decline, Magtein should be taken daily for maximum effectiveness.

How do most people notice a difference?

The double blind, placebo-controlled human study will be able to provide more details to this question. Based on qualitative feedback, some reported seeing benefits the first day while others took weeks to feel any difference. People have also reported greater recall, improved focus, better judgment, a reduction in the “after lunch sleepiness”, feeling more relaxed, more energy, more control, and being in better mood, etc.

How does it differ from what is already on the market?

Magtein is a completely revolutionary brain product. The animal study shows that it helps maintain the health of the neuron cells and increases neural plasticity. No other supplement has been shown to maintain health in these vital areas. Most products on the market for brain health do very little to maintain memory and cognitive function. The typical brain or memory product tries to stimulate brain activity through chemicals, while Magtein helped keep the brain structures healthy. Magtein is a result of 10-years of research at MIT that works at the root cause of cognitive function. Magtein is a unique product that brings enough magnesium to the brain to be functional. In both young and aged animals, Magtein was shown to increase memory and cognitive functions by elevating brain’s magnesium levels. No other product can make that claim.

Where can I buy products containing Magtein?

Thank you for your interest in Magtein. AIDP, Inc. provides the raw ingredient in bulk to manufacturers. Finished products are available through several on line companies and retail outlets. Listed below are a few for you to consider. Thank you again for your interest in Magtein.

Product Manufacturer Where To Buy
Swanson Ultra Magtein Magnesium l-threonate Swanson’s Vitamins swansonsvitamins.com
Neuro-Mag Magnesium l-thronate Life Extensions lef.org
MagMind Jarrow Amazon.com and select retailers
Magtein Magnesium l-threonate Vitacost vitacost.com
Brain Awakening Redd Remedies reddremedies.com and select retailers
Cognizone Progressive Labs progressivelabs.com
MindMax Nature’s Sunshine naturessunshine.com
Best Brain Magnesium Dr.’s Best drbvitamins.com
Magtein Source Naturals www.sourcenaturals.com and other websites
Neural Magtein Magceutics www.magceutics.com
Pure Encapsulations CogniMag Health Practitioners
MagTech Natural Stacks Naturalstacks.com

These statements have not been evaludated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

interviewWatch the complete interview with Dr. Gu.

interviewAn interview with Dr. Liu

interviewDr. Liu talks about the importance of Magnesium to cognitive function.